I'm not a huge bread-eater, but once in awhile I will indulge. I don't go the traditional route of white or wheat, but instead pick up a loaf of Ezekiel Bread found in the Freezer in the natural section of Carrs and Fred Meyer.
Ezekiel bread is a flourless organic bread that is made with whole grains and ranks a 36 on the Glycemic Index. The Glycemic Index is a useful tool to gauge how different foods affect our blood sugar levels. Any foods lower than 55 are considered "low glycemic." This is important for diabetics as well as those trying to lose excess body fat.
Consuming low-glycemic foods ensures that our energy levels stay consistent throughout the day and we are able to bypass the mid-day "crash." Spiking of the blood sugar by eating high glycemic foods, (ie. candy, white processed foods, fruit juice, etc.) means that the hormone insulin will rise as well. This should be avoided, as raising insulin like a roller-coaster all day will almost guarantee food will be stored as body fat. Raising insulin consistently can also cause insulin resistance which may lead to metabolic syndrome and diabetes in some folks.
Bread is good, there's no doubt about it. It doesn't have to be avoided if you are trying to lose weight, just pick a healthier option. Ezekiel bread comes in several flavors, so experiment to see which ones you like best.